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Wednesday 20 November 2013

ICMR & ICFRE to begin joint research to find novel sources of compounds against cancer, diabetes

The Indian Council of Medical Research (ICMR) and the Indian Council of Forestry Research and Education (ICFRE) will cooperate and initiate joint action for the exploration of forest resources for their bioactive principles (natural products), utilisation, promotion and adding value to the industrially valuable non-wood forest produce such as medicinal plants, herbs, shrubs, weeds, trees and medicinal fungi.
The collaborative research programme will help in finding out novel sources of compounds/ products active against cancer, diabetes and other diseases of public health importance.
The cooperation between the two premier research institutions in the country aims for phytochemical and pharmacological screening of Indian medicinal plants and medicinal fungi for two types of biological activities vis anti-cancer and anti-diabetic activity; and pre-clinical development of bioactive natural products and their analogues as chemotherapeutic agents.
Major strategies of this cooperation between the ICMR and ICFRE include bioactivity and mechanism of action directed isolation and characterisation of active known or novel molecules from plants and fungal resources; testing of compounds/ extracts/fractions/ biomass for clinical applications; rational drug-design-modification and analog synthesis; mechanism of action studies; sharing of research findings and technologies; exchange of academic materials and other information; and joint research activities and publications.
For this purpose, a memorandum of understanding (MoU) has been signed between the ICMR and the ICFRE.
Under the MoU, the roles and responsibility of the ICFRE include collection and identification of plants/ fungi/ other therapeutic/ nutritive agents; isolation of extracts/ fractions/ pure compounds/ biomass; characterisation of active known or novel molecules from plants and fungal resources; and exchange of academic materials and other information.
As per the agreement, it will be the responsibility of ICMR for screening and evaluation of extracts/ fractions/ pure compounds/ biomass to cure diseases of public health importance; bioactivity-and-mechanism of action studies of chemical entities; rational drug-design-modification and analog synthesis; and exchange of academic materials and other information.
The collaboration between the ICMR and the ICFRE is significant because despite many important past contributions from the plant kingdom, numerous plant species still remain to be explored for their bioactive principles. Adding value to natural products through identification, isolation, characterisation of novel compounds or agents in treatment of diseases of public health importance is the best way to protest the society and thus efforts need to be focused in this direction to realise the full potential of forest resource.
Source:Pharmabiz

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