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Monday, 6 July 2015

Tel Aviv & Harvard Universities Develop New Technology that Replenishes Skin’s Collagen

A non-invasive technique that harnesses pulsed electric fields to generate new skin tissue has been developed by researchers.

A team of researchers from Tel Aviv University (TAU) and Harvard Medical School developed the novel non-invasive technique that utilizes microsecond-pulsed, high voltage, non-thermal electric fields to produce scar-free skin rejuvenation. 

Lead researcher Alexander Golberg from TAU, said, "Our new application may jumpstart the secretion of new collagen and capillaries in problematic skin areas."

In the US since 2000, Botulium toxin, commonly known as botox, has been used to soothe lines and wrinkles to rejuvenate aging face. But botox injections are temporary and carry many risks, some neurological, said researchers. 

Current treatment to rejuvenate skin use physical and chemical methods to affect cells and extracellular matrix, but they induce scars. 

The new technique, pulse electric field technology affects only the cell membrane and preserves the extracellular matrix and releases multiple growth factors to spark new cell and tissue growth.

Pulse electric fields induce nanoscale defects on the cell membrane that cause the death of a small number of cells in affected areas. The released growth factors increase the metabolism of the remaining cells, generating new tissue.  

"The technique may revolutionize the treatment of degenerative skin diseases, researchers said. Pulsed electrical field technology has many advantages, which have already proved effective - for example, in food preservation, tumor removal, and wound disinfection," said Golberg.

To test the safety and efficacy if the technology in humans, researchers are developing a lo-cost device for use in clinical trials. 

The findings are published in the journal Scientific Reports. 


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